147201-04-5
- Product Name:DMT-2'-O-TBDMS-G(iBu)-CE-Phosphoramidite
- Molecular Formula:C50H68 N7 O9 P Si
- Purity:99%
- Molecular Weight:970.191
Product Details;
CasNo: 147201-04-5
Molecular Formula: C50H68 N7 O9 P Si
Top Quality DMT-2'-O-TBDMS-G(iBu)-CE-Phosphoramidite 147201-04-5 Hot Sell In Stock
- Molecular Formula:C50H68N7O9PSi
- Molecular Weight:970.191
- PKA:9.16±0.20(Predicted)
- PSA:197.90000
- LogP:9.76198
147201-04-5 Relevant articles
Microwave-assisted preparation of nucleoside-phosphoramidites
Meher,Efthymiou,Stoop,Krishnamurthy
supporting information, p. 7463 - 7465 (2014/07/07)
Microwave-assisted phosphitylation of st...
Overcoming hydrolytic sensitivity and low solubility of phosphitylation reagents by combining ionic liquids with mechanochemistry
Hardacre, Christopher,Huang, Haifeng,James, Stuart L.,Migaud, Marie E.,Norman, Sarah E.,Pitner, William R.
supporting information; experimental part, p. 5846 - 5848 (2011/06/26)
Ionic liquids have been used in combinat...
c-di-GMP displays A monovalent metal ion-dependent polymorphism
Zhang, Zhaoying,Gaffney, Barbara L.,Jones, Roger A.
, p. 16700 - 16701 (2007/10/03)
Cyclic diguanosine monophosphate (c-di-G...
Methods of producing phosphitylated compounds
-
Page 6-7, (2008/06/13)
Provided are methods of producing phosph...
147201-04-5 Process route
-
-
102691-36-1
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite
-
-
81279-39-2
N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
-
-
147201-04-5,131289-18-4,131316-87-5
N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tertbutyl(dimethylsilyl)guanine-3'-O-[O-(2-cyanoethyl)-N,N-(diisopropyl)]phosphoramidite
| Conditions | Yield |
|---|---|
|
With
pyridinium trifluroacetate;
In
nitromethane;
at 20 ℃;
for 5h;
|
97% |
|
With
pyridine hydrochloride;
In
dichloromethane;
at 65 ℃;
for 0.25h;
Reagent/catalyst;
Inert atmosphere;
Microwave irradiation;
Sealed tube;
|
44% |
-
-
124482-92-4,89992-70-1
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine
-
-
81279-39-2
N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
-
-
147201-04-5,131289-18-4,131316-87-5
N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tertbutyl(dimethylsilyl)guanine-3'-O-[O-(2-cyanoethyl)-N,N-(diisopropyl)]phosphoramidite
| Conditions | Yield |
|---|---|
|
With
N-ethyl-N,N-diisopropylamine;
for 0.5h;
Ionic liquid;
ball miling;
|
89% |
147201-04-5 Upstream products
-
102691-36-1
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite
-
81279-39-2
N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
-
124482-92-4
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine
-
108-18-9
diisopropylamine
147201-04-5 Downstream products
-
1220703-64-9
5'-O-DMTr-rG(iBu)p(CNE)-rA(Bz)po(CNE)dT-3'-O-Lev
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