147201-04-5

  • Product Name:DMT-2'-O-TBDMS-G(iBu)-CE-Phosphoramidite
  • Molecular Formula:C50H68 N7 O9 P Si
  • Purity:99%
  • Molecular Weight:970.191
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Product Details;

CasNo: 147201-04-5

Molecular Formula: C50H68 N7 O9 P Si

Top Quality DMT-2'-O-TBDMS-G(iBu)-CE-Phosphoramidite 147201-04-5 Hot Sell In Stock

  • Molecular Formula:C50H68N7O9PSi
  • Molecular Weight:970.191
  • PKA:9.16±0.20(Predicted) 
  • PSA:197.90000 
  • LogP:9.76198 

147201-04-5 Relevant articles

Microwave-assisted preparation of nucleoside-phosphoramidites

Meher,Efthymiou,Stoop,Krishnamurthy

supporting information, p. 7463 - 7465 (2014/07/07)

Microwave-assisted phosphitylation of st...

Overcoming hydrolytic sensitivity and low solubility of phosphitylation reagents by combining ionic liquids with mechanochemistry

Hardacre, Christopher,Huang, Haifeng,James, Stuart L.,Migaud, Marie E.,Norman, Sarah E.,Pitner, William R.

supporting information; experimental part, p. 5846 - 5848 (2011/06/26)

Ionic liquids have been used in combinat...

c-di-GMP displays A monovalent metal ion-dependent polymorphism

Zhang, Zhaoying,Gaffney, Barbara L.,Jones, Roger A.

, p. 16700 - 16701 (2007/10/03)

Cyclic diguanosine monophosphate (c-di-G...

Methods of producing phosphitylated compounds

-

Page 6-7, (2008/06/13)

Provided are methods of producing phosph...

147201-04-5 Process route

N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite
102691-36-1

N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite

N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
81279-39-2

N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tertbutyl(dimethylsilyl)guanine-3'-O-[O-(2-cyanoethyl)-N,N-(diisopropyl)]phosphoramidite
147201-04-5,131289-18-4,131316-87-5

N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tertbutyl(dimethylsilyl)guanine-3'-O-[O-(2-cyanoethyl)-N,N-(diisopropyl)]phosphoramidite

Conditions
Conditions Yield
With pyridinium trifluroacetate; In nitromethane; at 20 ℃; for 5h;
97%
With pyridine hydrochloride; In dichloromethane; at 65 ℃; for 0.25h; Reagent/catalyst; Inert atmosphere; Microwave irradiation; Sealed tube;
44%
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine
124482-92-4,89992-70-1

2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine

N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
81279-39-2

N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tertbutyl(dimethylsilyl)guanine-3'-O-[O-(2-cyanoethyl)-N,N-(diisopropyl)]phosphoramidite
147201-04-5,131289-18-4,131316-87-5

N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tertbutyl(dimethylsilyl)guanine-3'-O-[O-(2-cyanoethyl)-N,N-(diisopropyl)]phosphoramidite

Conditions
Conditions Yield
With N-ethyl-N,N-diisopropylamine; for 0.5h; Ionic liquid; ball miling;
89%

147201-04-5 Upstream products

  • 102691-36-1
    102691-36-1

    N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite

  • 81279-39-2
    81279-39-2

    N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

  • 124482-92-4
    124482-92-4

    2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine

  • 108-18-9
    108-18-9

    diisopropylamine

147201-04-5 Downstream products

  • 1220703-64-9
    1220703-64-9

    5'-O-DMTr-rG(iBu)p(CNE)-rA(Bz)po(CNE)dT-3'-O-Lev

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