121058-88-6
- Product Name：DMT-2'-O-TBDMS-C(Ac)-CE-Phosphoramidite
- Molecular Formula：C47H64 N5 O9 P Si
- Purity：99%
- Molecular Weight：902.113
Product Details;
CasNo： 121058-88-6
Molecular Formula： C47H64 N5 O9 P Si
Quality Factory Sells Top Purity 99% DMT-2'-O-TBDMS-C(Ac)-CE-Phosphoramidite 121058-88-6 with Safe Delivery
- Molecular Formula:C47H64 N5 O9 P Si
- Molecular Weight:902.113
- PKA:10.16±0.20(Predicted)
- PSA：169.22000
- LogP:9.24958
121058-88-6 Relevant articles
Microwave-assisted preparation of nucleoside-phosphoramidites
Meher,Efthymiou,Stoop,Krishnamurthy
supporting information, p. 7463 - 7465 (2014/07/07)
Microwave-assisted phosphitylation of st...
Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives
-
, (2008/06/13)
The present invention provides methods f...
Methods for synthesizing nucleosides, nucleoside derivatives and non-nucleoside derivatives
-
, (2008/06/13)
The present invention provides methods f...
Methylamine Deprotection Provides Increased Yield of Oligoribonucleotides
Reddy, M. P.,Farooqui, Firdous,Hanna, Naeem B.
, p. 8929 - 8932 (2007/10/02)
Use of methylamine or methylamine/ammoni...
121058-88-6 Process route
-
-
124482-92-4,89992-70-1
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine
-
-
121058-85-3
5'-O-DMTr-2'-O-TBDMS-N4-acetylcytidine
-
-
121058-88-6
(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)met hoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl(2-cyanoethyl)diisopropylphosphoramidite
| Conditions | Yield |
|---|---|
|
With
N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran;
|
65% |
|
With
N-ethyl-N,N-diisopropylamine;
dmap;
In
tetrahydrofuran;
for 3h;
Ambient temperature;
|
-
-
102691-36-1
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite
-
-
121058-85-3
5'-O-DMTr-2'-O-TBDMS-N4-acetylcytidine
-
-
121058-88-6
(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)met hoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl(2-cyanoethyl)diisopropylphosphoramidite
| Conditions | Yield |
|---|---|
|
With
5-(ethylthio)-1H-tetrazole;
In
dichloromethane;
at 65 ℃;
for 0.25h;
Inert atmosphere;
Microwave irradiation;
Sealed tube;
|
50% |
121058-88-6 Upstream products
-
124482-92-4
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine
-
121058-85-3
5'-O-DMTr-2'-O-TBDMS-N4-acetylcytidine
-
40615-36-9
4,4'-dimethoxytrityl chloride
-
121058-82-0
N4-acetyl-5'-O-(4,4'-dimethoxytrityl)cytidine
121058-88-6 Downstream products
-
121058-85-3
5'-O-DMTr-2'-O-TBDMS-N4-acetylcytidine
-
897626-57-2
C45H62N5O8PSi
-
1174673-48-3
C62H80N13O12PSi
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