206055-75-6
- Product Name:DMT-2'-O-4'-C-Locked-T-CE-Phosphoramidite
- Molecular Formula:
- Purity:99%
- Molecular Weight:772.835
Product Details;
CasNo: 206055-75-6
99% Purity Commercial production DMT-2'-O-4'-C-Locked-T-CE-Phosphoramidite 206055-75-6 with Cheapest Price
- Molecular Formula:C41H49N4O9P
- Molecular Weight:772.835
- PKA:9.46±0.10(Predicted)
206055-75-6 Relevant articles
Preparation of LNA phosphoramidites
Pedersen, Daniel Sejer,Rosenbohm, Christoph,Koch, Troels
, p. 802 - 808 (2002)
A highly efficient method for the prepar...
NOVEL PROCESS FOR MAKING ALLOFURANOSE FROM GLUCOFURANOSE
-
Page/Page column 44; 116-118, (2019/12/15)
The present invention relates to the man...
Method for preparation of LNA phosphoramidites
-
, (2008/06/13)
The present invention relates to large s...
2'-O,4'-C-Methylene bridged nucleic acid (2',4'-BNA): synthesis and triplex-forming properties.
Obika,Uneda,Sugimoto,Nanbu,Minami,Doi,Imanishi
, p. 1001 - 1011 (2007/10/03)
For development of ideal antisense and a...
206055-75-6 Process route
-
-
102691-36-1
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite
-
-
206055-71-2
1-[(1R,4R,6R,7S)-4-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-6-yl]-5-methylpyrimidine-2,4-dione
-
-
206055-75-6
(1R,3R,4R,7S)-3-(thymine-1-yl)-1-(4,4′-dimethoxytrityloxy)-7-(2-cyanoethoxy(diisopropylamino)phosphinoxymethyl)-2,5-dioxabicyclo[2.2.1]heptane
| Conditions | Yield |
|---|---|
|
With
4,5-dicyano-1H-imidazole;
In
dichloromethane; acetonitrile;
at 20 ℃;
for 2h;
|
100% |
|
With
N,N-diisopropylamine tetrazolide;
In
tetrahydrofuran; acetonitrile;
at 20 ℃;
|
99% |
|
With
N,N-diisopropylamine tetrazolide;
In
tetrahydrofuran; acetonitrile;
at 20 ℃;
for 3h;
|
99% |
|
With
4,5-dicyano-1H-imidazole;
In
dichloromethane;
at 20 - 25 ℃;
for 22h;
Large scale;
|
93% |
-
-
124482-92-4,89992-70-1
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine
-
-
206055-71-2
1-[(1R,4R,6R,7S)-4-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-6-yl]-5-methylpyrimidine-2,4-dione
-
-
206055-75-6
(1R,3R,4R,7S)-3-(thymine-1-yl)-1-(4,4′-dimethoxytrityloxy)-7-(2-cyanoethoxy(diisopropylamino)phosphinoxymethyl)-2,5-dioxabicyclo[2.2.1]heptane
| Conditions | Yield |
|---|---|
|
With
N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
|
70% |
|
With
N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
for 1h;
|
70% |
206055-75-6 Upstream products
-
124482-92-4
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine
-
206055-71-2
1-[(1R,4R,6R,7S)-4-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-6-yl]-5-methylpyrimidine-2,4-dione
-
102691-36-1
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite
-
350505-61-2
2',3'-O-benzylidene-4'-(p-toluenesulfonyloxymethyl)uridine
206055-75-6 Downstream products
-
1004306-97-1
C52H62N5O16PSi
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