251647-55-9
- Product Name：DMT-2'-O-MOE-G(iBu)-CE-Phosphoramidite
- Molecular Formula：C47H60N7O10P
- Purity：99%
- Molecular Weight：914.008
Product Details;
CasNo： 251647-55-9
Molecular Formula： C47H60N7O10P
Perfect Factory Offer Excellent quality DMT-2'-O-MOE-G(iBu)-CE-Phosphoramidite 251647-55-9 with Safe Shipping
- Molecular Formula:C45H56N7O9P
- Molecular Weight:914.008
- PKA:9.16±0.20(Predicted)
- PSA：207.13000
- LogP:7.40318
251647-55-9 Relevant articles
Antisense modulation of polo-like kinase expression
-
Page/Page column 21, (2008/06/13)
Antisense compounds, compositions and me...
Antisense inhibition via RNAse H-independent reduction in mRNA
-
Page/Page column 20, (2010/02/12)
The present invention provides compositi...
Antisense modulation of PPP3CB expression
-
Page/Page column 21, (2008/06/13)
Antisense compounds, compositions and me...
Antisense modulation of perilipin expression
-
Page/Page column 21, (2008/06/13)
Antisense compounds, compositions and me...
251647-55-9 Process route
-
-
102691-36-1
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite
-
-
251647-50-4
5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine
-
-
251647-55-9
MOE G amidite
Conditions
| Conditions | Yield |
|---|---|
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide); toluene;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide); toluene;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide); toluene;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide); toluene;
at 20 ℃;
for 5h;
|
91% |
|
5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine;
In
DMF (N,N-dimethyl-formamide); toluene;
at 50 ℃;
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite;
With
1H-tetrazole;
In
1-methyl-1H-imidazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide); toluene;
at 20 ℃;
for 5h;
|
91% |
|
With
N-Methylpyrrole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite; 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine;
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
With
triethylamine;
In
DMF (N,N-dimethyl-formamide); water;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite; 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine;
With
1H-tetrazole;
In
hexane; ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile;
at 20 - 50 ℃;
With
1-methyl-1H-imidazole; triethanolamine;
In
DMF (N,N-dimethyl-formamide); water;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine;
In
DMF (N,N-dimethyl-formamide); toluene;
at 50 ℃;
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite;
With
1H-tetrazole;
In
1-methyl-1H-imidazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide); toluene;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite; 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine;
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
With
triethylamine;
In
DMF (N,N-dimethyl-formamide); water;
|
91% |
|
With
1-methyl-1H-imidazole; 5H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1H-tetrazole;
In
1-methyl-1H-imidazole; DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1H-tetrazole;
In
1-methyl-1H-imidazole; DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1H-tetrazole;
1-methyl-1H-imidazole;
In
N,N-dimethyl-formamide; toluene;
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
In
DMF (N,N-dimethyl-formamide);
at 20 ℃;
for 5h;
|
91% |
|
With
1-methyl-1H-imidazole; 1H-tetrazole;
at 20 ℃;
for 5h;
|
91% |
-
-
251647-55-9
MOE G amidite
Conditions
| Conditions | Yield |
|---|---|
|
|
251647-55-9 Upstream products
-
102691-36-1
N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite
-
251647-50-4
5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine
Relevant Products
-
benfooxythiamine
CAS：909542-99-0
-
DMT-2'-O-MOE-A(Bz)-CE-PhosphoramiditeCAS：251647-53-7
-
1,1,1-TRIFLUORO-5-METHYL-2,4-HEXANEDIONECAS：30984-28-2
