42348-86-7
- Product Name：5-Chloro-1-indanone
- Molecular Formula：C9H7ClO
- Purity：99%
- Molecular Weight：166.607
Product Details;
CasNo： 42348-86-7
Molecular Formula： C9H7ClO
Appearance： White crystal
High Quality Chinese Factory supply 42348-86-7 5-Chloro-1-indanone
- Molecular Formula:C9H7ClO
- Molecular Weight:166.607
- Appearance/Colour:White crystal
- Vapor Pressure:0.00233mmHg at 25°C
- Melting Point:94-98 °C(lit.)
- Refractive Index:1.6
- Boiling Point:288.5 °C at 760 mmHg
- Flash Point:129.4 °C
- PSA：17.07000
- Density:1.312 g/cm3
- LogP:2.46890
5-Chloro-1-indanone(Cas 42348-86-7) Usage
|
Preparation |
3-chlorobenzaldehyde as raw material first reacts with propionic acid to prepare 3-chloro-phenylpropionic acid, which is then subjected to Friedel-Crafts acylation reaction to prepare 5-chloro-1-indanone. Organic solvents of formic acid diethylamine participate in the first step, and the reaction temperature is 20-150℃. An organic solvent of methylene chloride and a catalyst of zinc chloride participate in the second step, and the reaction temperature is -10 to 80 ℃. Synthetic method of 5-chloro-1-indanone |
|
General Description |
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types. |
InChI:InChI=1/C9H7ClO/c10-7-2-3-8-6(5-7)1-4-9(8)11/h2-3,5H,1,4H2
42348-86-7 Relevant articles
New process for preparing 5-chloro-2,3-dihydro-1-indanone
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Paragraph 0030-0076, (2021/06/13)
The invention belongs to the technical f...
Synthesis method of 5-chloro-1-indanone
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Paragraph 0025-0044, (2021/07/10)
The invention relates to a synthesis met...
Preparation method for synthesizing 5-chloro-1-indanone through one-step method
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Sheet 0012-0014, (2021/10/27)
The invention provides a preparation met...
Preparation method of 5-chloro-1-indanone
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Paragraph 0007; 0037-0050, (2021/03/11)
The invention provides a preparation met...
42348-86-7 Process route
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3946-29-0
3,4'-Dichloropropiophenone
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-
42348-86-7
5-chloro-1-indanone
| Conditions | Yield |
|---|---|
|
With
aluminum (III) chloride; potassium chloride; sodium chloride;
at 130 ℃;
for 3h;
Temperature;
Reagent/catalyst;
|
75% |
|
With
Et3NHCl-1.8AlCl3 ionic liquid;
In
octane;
at 70 - 120 ℃;
Ionic liquid;
|
72% |
|
With
sulfuric acid;
|
70% |
|
at 130 ℃;
for 3h;
Temperature;
|
66% |
|
With
aluminium trichloride;
|
|
|
With
sulfuric acid;
|
|
|
With
sulfuric acid;
at 90 ℃;
|
|
|
With
aluminum (III) chloride;
|
-
-
7448-87-5
p-chlorophenyl vinyl ketone
-
-
42348-86-7
5-chloro-1-indanone
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
toluene;
at -5 - 10 ℃;
for 4h;
under 1500.15 - 1875.19 Torr;
Temperature;
Solvent;
|
95.1% |
42348-86-7 Upstream products
-
21640-48-2
3-chlorohydrocinnamic acid
-
3946-29-0
3,4'-Dichloropropiophenone
-
40478-50-0
3-(3-chlorophenyl)propionyl chloride
-
108-90-7
chlorobenzene
42348-86-7 Downstream products
-
132630-11-6
5-(benzylthio)-2,3-dihydro-1H-inden-1-one
-
33781-38-3
5-chloro-2,3-dihydro-1H-inden-1-ol
-
192702-71-9
1-bromo-5-chloroindane
-
511533-17-8
6-chloro-1-phenyl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxylic acid
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