1120329-48-7
- Product Name：UNA-U-CE Phosphoramidite
- Molecular Formula：
- Purity：99%
- Molecular Weight：852.921
Product Details;
CasNo： 1120329-48-7
Factory supply UNA-U-CE Phosphoramidite 1120329-48-7 with low price
- Molecular Formula:C46H53N4O10P
- Molecular Weight:852.921
1120329-48-7 Relevant articles
Selective biocatalytic acylation studies on 5-O-(4,4′- Dimethoxytrityl)-2,3-secouridine: An efficient synthesis of UNA monomer
Singh, Sunil K.,Reddy, L. Chandrashekhar,Srivastava, Smriti,Olsen, Carl E.,Sanghvi, Yogesh S.,Langkjaer, Niels,Wengel, Jesper,Parmar, Virinder S.,Prasad, Ashok K.
, p. 831 - 840 (2013/02/22)
Lipozyme TL IM (Theremomyces lanuginosus...
UNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability
Langkjaer, Niels,Pasternak, Anna,Wengel, Jesper
experimental part, p. 5420 - 5425 (2009/12/06)
UNA (unlocked nucleic acid) monomers are...
1120329-48-7 Process route
-
-
124482-92-4,89992-70-1
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine
-
-
2′-O-benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′,3′-secouridine
-
-
1120329-48-7
2'-O-benzoyl-3'-O-(2-cyanoethoxy(diisopropylamino)phosphino)-5'-O-(4,4'-dimethoxytrityl)-2',3'-secouridine
| Conditions | Yield |
|---|---|
|
With
N-ethyl-N,N-diisopropylamine;
In
acetonitrile;
at 20 ℃;
for 0.666667h;
Inert atmosphere;
|
68% |
|
With
N-ethyl-N,N-diisopropylamine;
In
acetonitrile;
at 25 - 28 ℃;
|
-
-
769-78-8,24991-32-0
vinyl benzoate
-
-
251943-33-6
5'-O-(4,4'-dimethoxytrityl)-2',3'-secouridine
-
-
1120329-48-7
2'-O-benzoyl-3'-O-(2-cyanoethoxy(diisopropylamino)phosphino)-5'-O-(4,4'-dimethoxytrityl)-2',3'-secouridine
| Conditions | Yield |
|---|---|
|
Multi-step reaction with 2 steps
1: Theremomyces lanuginosus lipase immobilized on silica / toluene / 3 h / 40 - 42 °C / Enzymatic reaction
2: N-ethyl-N,N-diisopropylamine / acetonitrile / 25 - 28 °C
With
N-ethyl-N,N-diisopropylamine;
In
toluene; acetonitrile;
|
1120329-48-7 Upstream products
-
124482-92-4
2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine
-
769-78-8
vinyl benzoate
-
251943-33-6
5'-O-(4,4'-dimethoxytrityl)-2',3'-secouridine
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